There is so much we can do to inhibit iron absorption for Hereditary Hemochromatosis.

A Hemochromatosis Diet is essential to lower your ferritin and require less phlebotomy’s.

Tannins in Teas:

Black Tea has the highest concentration of tannins ranging from 11.76% to 15.14%
Green Tea has an average of 2.65% to 3.11%

Oolong tea is about 8.66%

Studies from the NIH have shown that drinking black tea with your meals significantly reduces iron absorption.

Natural Iron Chelators to add to your tea: Peppermint, Cocoa, Chili Powder, Raspberry, Blackberry, apple, and Rosemary.

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  • Gastric acid inhibitors PPI’s Proton Pump Inhibitors: Reduce stomach acid Prescription: esomeprazole (Nexium), omeprazole (Prilosec), lansoprazole (Prevacid, and others) and pantoprazole (Prontonix)
  • Many studies have been done on the effects of patients taking PPI’s vs patients not taking PPI’s. Science Direct study showed over 2 years the group taking PPI’s had 1.25 to 3.17 phelbotomy’s per year vs 3.0 to 5.0 per year.
  • Probiotics have the same effect but are more natural:
  • Quercetin flavanol quercetin has been shown to reduce iron. It is especially enriched in onions, tea and apples (Pectin)

Resveratrol

Binds to iron and reduces its absorption from food. It also has other benefits, including:
  • Liver protection and Resveratrol can reduce iron deposition in the liver, which can lead to toxicity. It can also improve liver function in mice with iron overload.
  • Cardiomyopathy: Resveratrol can reduce iron-induced oxidative stress and myocardial fibrosis in cardiomyocytes and cardio fibroblasts.
  • Liver fibrosis Resveratrol can reduce liver fibrosis caused by iron overload. It does this by regulating iron homeostasis, reducing iron uptake, and increasing iron export.
  • Vitamin E and selenium function synergistically in the myocardium to provide important antioxidant defenses in iron-overload states, including increased concentrations of selenium, increased glutathione peroxidase activity and decreased concentrations of iron. Resource NIH
  • Turmeric is among the spices known to inhibit iron absorption by 20%-90% in humans, reducing iron absorption in a dose-dependent manner [10]. The stoichiometric qualities of turmeric indicate it could bind nearly all absorbable iron and cause iron deficiency. Resource NIH

Soybean Protein inhibits Heme Iron by 53% by taking 25mg Source NIH:

If you’re a red meat eater try to incorporate more Soybean Protein.

  • 3 ounces water-packed tofu — 6 to 13 grams
  • 3 ounces silken tofu — 6 grams
  • 8 ounces plain soy milk — 3 to10 grams
  • 8 ounces Edensoy Extra Plain soy milk — 10 grams
  • 8 ounces vanilla soy milk — 3 to 6 grams
  • 1/4 cup (1 ounce) soy nuts — 12 grams
  • 2 tablespoons soy nut butter — 6 to 8 grams
  • 1 soy burger — 10 grams
  • 1/2 cup (4 ounces) tempeh — 16 to 22 grams
  • 1/2 cup canned white soybeans — 13 grams
  • 1/2 cup canned black soybeans — 11 grams
  • 2/3 cup (3 ounces) edamame — 6 grams
  • 2/3 cup green (sweet) soybeans — 7 to 9 grams
  • 1/2 cup rehydrated textured vegetable protein (TVP) — 12 grams

Egg Whites

(1) Inhibits iron by 27% Source NIH

Calcium

does of 1,000 mg or more reduces non heme iron by 49.6%, and 800mg or more reduces the heme iron absorption by 37.7%.

Phytates

  • These natural plant compounds can bind to iron and prevent it from being absorbed.
  • A popular supplemental form of phytate is IP-6. Wheat, oats, and rice
  • Legumes: Black beans, pinto beans, kidney beans, soybeans, peanuts, and lentils
  • Nuts and seeds: Walnuts, pine nuts, almonds, sesame seeds, linseeds, and sunflower seeds
  • Tubers: Potatoes, turnips, beets, and carrots

Phytates

can form complexes with zinc in the gastrointestinal tract, which can reduce the absorption of zinc. However, phytates also have antioxidant properties and may protect against DNA damage and cancer cell growth.

Pectin

apples, oranges, lemons and limes have the highest content of Pectin. Pectin supplements This indigestible fiber binds to non-heme iron and makes it harder for the body to absorb.

Curcumin

Preclinical studies suggest that curcumin can reduce iron-catalyzed oxidative damage to DNA and the liver.

Alpha lipoic acid

Preclinical studies suggest that alpha lipoic acid may reduce brain iron levels in older rats.

Carnitine

Derivatives are antioxidants that may help with oxidative damage caused by iron overload.

Chia seeds, hemp, and flax

In one study, chia seeds reduced iron accumulation in the blood by 54.47%.

Coenzyme Q10

• In one study, coenzyme Q10 reduced iron accumulation in the blood by 54.53%.
• In addition to supplements, some evidence suggests that selenium and vitamin E may help protect against iron-overload-related heart muscle damage.

Flavonoids

• They are abundant in fruits, vegetables, tea, wine, seeds, and plant roots. Many flavonoids have antitussive, expectorant, antiasthmatic, and antibacterial properties. In addition, flavonoids exert the same effect as phytoestrogens. They also have iron chelating and antioxidative properties. B12 Injections and Vitamin B9 supplements help produce red blood cells which are depleted during a phlebotomy.

HMBD3

• Tests show patients with hemochromatosis do not absorb as much Vitamin D from foods.

You can also do injections of Vitamin D

B12 This is SO important, because it restores your red blood cells. It is especially needed before and after phlebotomy’s. You can take pills but injections work much faster and will give you more energy.

If you do not want to do injections we recommend the liquid

WARNING: Milk Thistle & NAC’s are often considered iron inhibitors, please read carefully.

  • Milk Thistle: A study done by The national library of medicine shows that patients with the C282Y mutation should not take Milk Thistle. The clinical trials showed that is exacerbated iron levels.
  • N-Acetyl Cysteine NAC’s: Should be avoided if you have iron issues because it can accelerate free radical production. Cysteine, which is a component of NAC, can support glutathione, but it can backfire and increase free radical production if there’s too much iron in the body. The national library of medicine

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